2-氨基-4-甲氧基-5-[3-(4-吗啉基)丙氧基]-苯甲酰胺
Gefitinib impurity 2
CAS: 246512-44-7
Molecular Formula: C15H23N3O4
2-氨基-4-甲氧基-5-[3-(4-吗啉基)丙氧基]-苯甲酰胺 - Names and Identifiers
2-氨基-4-甲氧基-5-[3-(4-吗啉基)丙氧基]-苯甲酰胺 - Physico-chemical Properties
| Molecular Formula | C15H23N3O4 |
| Molar Mass | 309.36 |
| Density | 1.208±0.06 g/cm3(Predicted) |
| Melting Point | 153.5 °C |
| Boling Point | 460.6±45.0 °C(Predicted) |
| pKa | 15.86±0.50(Predicted) |
| Storage Condition | 2-8°C，密封，干燥 |
2-氨基-4-甲氧基-5-[3-(4-吗啉基)丙氧基]-苯甲酰胺 - Reference Information
| biological activity | Gefitinib importance 2 is an impurity of Gefitinib. Gefitinib (HY-50895) is a potent, orally active selective EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 54 nM) and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib can also induce autophagy in cells. Gefitinib has anti-tumor activity. |
Last Update：2024-04-09 15:16:57
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2-氨基-4-甲氧基-5-[3-(4-吗啉基)丙氧基]-苯甲酰胺
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西洛他唑相关物质C USP标准品
METHYL PENT-4-YN-2-YLCARBAMATE
(3-甲基-5-硝基苯基)硼酸
PYROTARTARIC ANHYDRIDE
三甲基乙氧基硅烷
-(D-5-氨基-5-羧基戊酰胺基)头孢霉烷酸锌盐
己二酰亚胺酸二甲酯二盐酸盐[用于蛋白质研究的交联剂]
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依那普利欧洲药典杂质 D